Isoflupredone Combinations Topical

What is isoflupredone combinations topical?

Isoflupredone combinations topical are combination medications containing isoflupredone (a corticosteroid) and other medications. Isoflupredone may be compounded with an antibiotic, a local anesthetic, or other medications to treat surface skin conditions where use of a steroid combination product is indicated.

Its use may be off label (extra label) depending on the species, condition(s) being treated, and formulation. Many drugs are commonly prescribed for off-label use in veterinary medicine. “Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions carefully, as they may be significantly different from those on the label.

How do I give my pet isoflupredone combinations topical?

Isoflupredone combinations come in powder format and ointment forms, often compounded.

• All forms are applied topically directly on the skin. 
• Clean the affected area as directed by your veterinarian before applying the medication. 
• Do not allow the tip of the bottle to touch affected areas.
• Wash your hands after application and avoid contact with eyes, mouth, and nose.
• Do not allow your pet to lick or groom the affected area for at least 30 minutes after application.
• Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears your pet is feeling better.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects from isoflupredone combinations topical?

Isoflupredone combinations topical may cause the following side effects:

• redness and/or swelling at site of application
• thinning of fur or fur loss 
• decreased energy level or appetite, vomiting, diarrhea
• increased thirst 

The following reactions are rare, but if they occur, contact your veterinarian immediately:

• an allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. Isoflupredone is a moderate-acting medication and should stop working within a few days but may take longer in pets with kidney or liver disease. Effects may last longer depending on the medications in the combination product.

Are there any risk factors for this medication?

Isoflupredone should NOT BE USED in pets that:

• are allergic to any component
• have tuberculosis skin infections

Isoflupredone should be USED WITH CAUTION when treating pets that:

• have small body size
• need treatment of large areas
• are pregnant or nursing

Are there any drug interactions I should be aware of?

No known drug interactions have been reported for this combination medication, though certain medications may interact with the individual drugs in this combination medication.

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

• Your veterinarian may schedule a follow-up visit for after the course of medication is complete to ensure the infection has been cleared and/or do additional testing to ensure this is the right medication for the infection present. In this case, follow your veterinarian’s directions.
• At home, monitor for any abnormal changes. If these occur, discontinue the medication and contact your veterinarian.

How do I store isoflupredone combinations topical?

• Store the medication in its original container, protected from moisture, at room temperature. 
• Keep the cap tightly closed.
• Follow storage and expiration recommendations for specially compounded formulas.
• Keep medication out of reach of children and pets.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Adverse effects should also be reported to the FDA or Health Canada.